Therefore, this analysis occupies an important place in evidence-based medicine. Meta-analysis allows the results of several independent studies to be combined and assessed unbiasedly. The main feature of evidence-based medicine is a critical appraisal of the available evidence. This understanding led to the development of evidence-based medicine, an approach to medical practice in which decisions about any medical intervention are made based on available evidence of effectiveness and safety, with such evidence being evaluated, compared, summarised, and widely disseminated for the benefit of patients. And often, the results of these studies are contradictory, complicating clinical decision-making. Multiple research groups in different parts of the world study many medical issues simultaneously. The importance of meta-analysis in evidence-based medicine Determination of the informativeness of the main results by sensitivity analysis. ![]() These types of heterogeneity may make it impossible to generalise the data in a meta-analysis. When applied to meta-analyses, heterogeneity refers to differences between studies, which may be due to the use of different methods of statistical data processing (statistical heterogeneity) or to differences in key characteristics of participants, interventions used, clinical outcomes, or criteria for their evaluation (clinical heterogeneity). Assessing the heterogeneity (heterogeneity) of the meta-analysis.Examining all studies on the problem in question eliminates the influence of studies and opinions that are more popular at a given time.In doing so, a qualitative meta-analysis involves: For this purpose, the results of two or more randomised controlled trials are combined.Ī meta-analysis uses statistical methods to obtain an overall estimate of the effect. Most often, it is used to assess the clinical effectiveness of therapeutic interventions. Meta-analysis is a scientific research methodology consisting of the analysis and synthesis (combination) of data obtained from previously conducted independently from each other studies on the same problem. Why meta-analysis data are so important is discussed in this article. Most clinicians begin searching for the best, evidence-based evidence to make informed decisions by visiting the Cochrane Library, which is regularly updated with more and more meta-analyses and systematic reviews. They are an integral part of evidence-based medicine. ![]() Meta-analysis and systematic review are at the top of the hierarchy of evidence for data reliability in various types of biomedical research.
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